Cell Metabolism
The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis
2015 · PMID 25738459
Lee C et al.
View sourceCompound information
Molecular profile
Technical specifications for laboratory reference
Molecular profile
What is MOTS-C?
Mitochondrial open reading frame of the 12S rRNA-c — a 16-amino-acid mitochondrial-derived peptide (MDP) encoded in mtDNA, studied in AMPK and metabolic homeostasis research.
- Type
- Mitochondrial-derived peptide
- CAS Number
- 1627580-64-6
- Molecular Weight
- 2,174.6 g/mol
- Amino Acids
- 16
- Sequence
- Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
- Formula
- C₁₀₁H₁₅₂N₂₈O₂₂S₂
Storage requirements
Stability information
Protect from lightAvoid repeated freeze-thaw
Lyophilized (powder)
−20°C · up to 24 months
Reconstituted
2–8°C · up to 14 days
Literature
Sources & references
Peer-reviewed research for laboratory background
Nature Communications
The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity
2021 · PMID 33479233
Reynolds JC et al.
View sourceCitations are provided for research background only. Peptide Club materials are sold for laboratory research use — not for human or veterinary consumption. References do not constitute product claims.
